KROK 1 2018 – Question 130 · KROK (Medicine) · Biological Chemistry

During hypersensitivity skin test a patient received an allergen subcutaneously, after which the patient developed skin redness, edema, and pain due to histamine action. This biogenic amine is produced as the result of the following transformation of histidine amino acid:

  1. A. Decarboxylation
  2. B. Phosphorylation
  3. C. Isomerization
  4. D. Deaminization
  5. E. Methylation
Hint

Compare the structures of histidine and histamine and ask what chemical change converts an amino acid into its biogenic amine.

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