KROK 1 2018 – Question 150 · KROK (Medicine) · Biological Chemistry
A newborn presents with weak suckling, frequent vomiting, and hypotonia. Blood and urine citrulline are very high. What metabolic process is disturbed?
- A. Tricarboxylic acid cycle
- B. Ornithine cycle
- C. Gluconeogenesis
- D. Glycolysis
- E. Cori cycle
Hint
Ask in which metabolic route the amino acid that accumulates is an intermediate, and which toxic nitrogen compound would build up when that route is blocked in a newborn.
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