KROK 1 2018 – Question 129 · KROK (Medicine) · Biological Chemistry

A hereditary disease - homocystinuria - is caused by disturbed transformation of homocysteine into methionine. Accumulated homocysteine forms its dimer (homocystine) that can be found in urine. What vitamin preparation can decrease homocysteine production?

  1. A. Vitamin B2
  2. B. Vitamin C
  3. C. Vitamin PP
  4. D. Vitamin B12
  5. E. Vitamin B1
Hint

Identify the coenzyme needed by the enzyme that remethylates homocysteine, then match it to the vitamins listed.

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