KROK 1 2011 – Question 168 · KROK (Medicine) · Biological Chemistry

A male patient has been diagnosed with acute radiation disease. Laboratory examination revealed a considerable reduction of platelet serotonin level. The likely cause of platelet serotonin reduction is the disturbed metabolism of the following substance:

  1. A. Phenylalanine
  2. B. Serine
  3. C. 5-oxytryptofane
  4. D. Tyrosine
  5. E. Histidine
Hint

Trace the biosynthetic route of serotonin back to its amino-acid precursor and ask which listed compound lies directly on that route.

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