KROK 1 2012 – Question 2 · KROK (Medicine) · Biological Chemistry

Characteristic sign of glycogenosis is muscle pain during physical work. Blood examination reveals usually hypoglycemia. This pathology is caused by congenital deficiency of the following enzyme:

  1. A. Alpha amylase
  2. B. Glucose 6-phosphate dehydrogenase
  3. C. Lysosomal glycosidase
  4. D. Glycogen phosphorylase
  5. E. Gamma amylase
Hint

Think about the enzymatic step that mobilises stored polysaccharide for energy, and why both working muscle and blood glucose would suffer if that step were missing.

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