KROK 1 2011 – Question 172 · KROK (Medicine) · Biological Chemistry
A child has mental and physical retardation, grave damage of internal connective tissue. Urine analysis reveals keratan sulfates. What metabolic process is disturbed?
- A. Elastin
- B. Glycosaminoglycans
- C. Collagen
- D. Fibronectin
- E. Hyaluronic acid
Hint
Think about which class of connective-tissue ground-substance macromolecules includes keratan sulfate and what a defect in their lysosomal degradation would do.
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