KROK 1 2011 – Question 167 · KROK (Medicine) · Biological Chemistry
A newborn child was found to have reduced intensity of sucking, frequent vomiting, hypotonia. Urine and blood exhibit increased concentration of citrulline. What metabolic process is disturbed?
- A. Cori cycle
- B. Ornithinic cycle
- C. Glycolysis
- D. Tricarboxylic acid cycle
- E. Glyconeogenesis
Hint
Ask which liver pathway for disposal of nitrogen uses citrulline as an intermediate, and what accumulates and harms the brain when it is blocked.
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