KROK 1 2012 – Question 7 · KROK (Medicine) · Biological Chemistry
A 46-year-old female patient has a continuous history of progressive muscular (Duchenne’s) dystrophy. Which blood enzyme changes will be of diagnostic value in this case?
- A. Glutamate dehydrogenase
- B. Creatine phosphokinase
- C. Lactate dehydrogenase
- D. Pyruvate dehydrogenase
- E. Adenylate cyclase
Hint
Ask which enzyme, abundant in skeletal muscle fibres, would escape into the serum when the fibre membrane is fragile and leaky, and how specific it is for muscle.
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