KROK 1 2015 – Question 88 · KROK (Medicine) · Biological Chemistry

In case of alkaptonuria, homogentisic acid is excreted in urine in large amounts. The development of this disease is associated with metabolic disorder of the following amino acid:

  1. A. Methionine
  2. B. Tyrosine
  3. C. Phenylalanine
  4. D. Alanine
  5. E. Asparagine
Hint

Trace the degradation pathway in which homogentisic acid is an intermediate, and ask which amino acid sits immediately upstream of it.

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