KROK 1 2015 – Question 76 · KROK (Medicine) · Biological Chemistry

An unconscious patient was delivered by ambulance to the hospital. On objective examination the patient was found to present no reflexes, periodical convulsions, irregular breathing. After laboratory examination the patient was diagnosed wi- th hepatic coma. Disorders of the central nervous system develop due to accumulation of the following metabolite:

  1. A. Ammonia
  2. B. Bilirubin
  3. C. Urea
  4. D. Glutamine
  5. E. Histamine
Hint

Think about the toxic nitrogen-containing compound that the healthy liver normally clears from the blood, and how its build-up would affect neurons.

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