KROK 1 2014 – Question 99 · KROK (Medicine) · Biological Chemistry
Degenerative changes in posterior and lateral columns of spinal cord (funicular myelosis) caused by methylmalonic acid accumulation occur in patients with B₁₂-deficiency anemia. This results in synthesis disruption of the following substance:
- A. Serotonin
- B. Norepinephrine
- C. Myelin
- D. Acetylcholine
- E. Dopamine
Hint
Ask which component of the spinal cord tracts depends on normal fatty acid synthesis, and what accumulating methylmalonic acid would do to it.
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