KROK 1 2014 – Question 90 · KROK (Medicine) · Biological Chemistry

In case of alkaptonuria, homogentisic acid is excreted in urine in large amounts. The development of this disease is associated with a disorder of metabolism of the following amino acid:

  1. A. Phenylalanine
  2. B. Alanine
  3. C. Methionine
  4. D. Tyrosine
  5. E. Asparagine
Hint

Homogentisic acid is an intermediate of a catabolic pathway; ask which amino acid's degradation passes through it and where that pathway is blocked.

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