KROK 1 2014 – Question 134 · KROK (Medicine) · Biological Chemistry
A newborn baby has numerous hemorrhages. Blood coagulation tests reveal increased prothrombin time. The child is most likely to have a disorder of the following biochemical process:
- A. Production of gamma-carboxyglutamate
- B. Hydroxylation of proline
- C. Conversion of methylmalonyl CoA to succinyl CoA
- D. Degradation of glutathione
- E. Conversion of homocysteine to methionine
Hint
Ask which clotting factors are measured by prothrombin time and which vitamin-dependent step they need before they become active; think also about the newborn gut.
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