KROK 1 2014 – Question 122 · KROK (Medicine) · Biological Chemistry
For biochemical diagnostics of myocardial infarction it is necessary to measure activity of a number of enzymes and their isoenzymes. What enzymatic test is considered to be the best to prove or disprove the diagnosis of infarction in the early period after the chest pain is detected?
- A. LDH1 lactate dehydrogenase isoenzyme
- B. LDH2 lactate dehydrogenase isoenzyme
- C. Creatine kinase isoenzyme CK-MB
- D. Aspartate aminotransferase cytoplasmic isoenzyme
- E. Creatine kinase isoenzyme CK-MM
Hint
Weigh two properties of each test: how specific the isoenzyme is for the myocardium, and how soon after the onset of pain its activity rises in the blood.
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