KROK 1 2014 – Question 70 · KROK (Medicine) · Biological Chemistry

A patient with homogentisuria has signs of arthritis, ochronosis. In this case, the pain in the joints is associated with the deposition of:

  1. A. Carbonates
  2. B. Oxalates
  3. C. Phosphates
  4. D. Homogentisates
  5. E. Urates
Hint

Ask which compound piles up because of the block in tyrosine degradation behind this condition, and what it does to collagen-rich cartilage once it is oxidized.

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