KROK 1 2013 – Question 62 · KROK (Medicine) · Pharmacology

Curariform substances introduced into a human body cause the relaxation of all skeletal muscles. What changes in the neuromuscular synapse cause this phenomenon?

  1. A. Blockade of N-cholinergic receptors of the synaptic membrane
  2. B. Depolarization of the postsynaptic membrane
  3. C. Blockade of Ca2+ channels of the presynaptic membrane
  4. D. Impaired acetylcholine release
  5. E. Impaired cholinesterase synthesis
Hint

Think about whether curare-like drugs interfere with the production and release of the transmitter or with its action on the muscle side of the synapse.

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