KROK 1 2013 – Question 110 · KROK (Medicine) · Pharmacology

A 66-year-old patient with Parkinson’s disease shows an improvement in locomotor activity after prolonged use of a certain drug which is converted to dopamine by the decarboxylation. What drug has the patient taken?

  1. A. Chlorpromazine
  2. B. Droperidol
  3. C. Levodopa
  4. D. Naloxone
  5. E. Celecoxib
Hint

Dopamine itself cannot cross the blood-brain barrier, so ask what kind of substance could reach the striatum and be converted there by the enzymatic step named in the stem.

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