KROK 1 2013 – Question 90 · KROK (Medicine) · Pharmacology

Despite the administration of cardiotonics and a thiazide diuretic a patient with chronic heart failure has persistent edemata, there is a risk of ascites. What medication should be administered in order to enhance the diuretic effect of the drugs used?

  1. A. Amiloride
  2. B. Furosemide
  3. C. Spironolactone
  4. D. Mannitol
  5. E. Clopamide
Hint

Ask which hormonal mechanism sustains sodium and water retention in chronic heart failure even on a thiazide, and how it could be blocked.

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