KROK 1 2013 – Question 60 · KROK (Medicine) · Pharmacology
It is known that individuals with genetically caused deficiency of glucose-6-phosphate dehydrogenase may develop RBC hemolysis in response to the administration of some antimalarial drugs. Manifestation of adverse reactions to drugs is called:
- A. Tachyphylaxis
- B. Tolerance
- C. Allergy
- D. Idiosyncrasy
- E. Sensibilization
Hint
Distinguish an abnormal reaction that rests on an inherited enzyme defect from reactions that need an immune mechanism or arise with repeated dosing.
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