KROK 1 2012 – Question 197 · KROK (Medicine) · Biological Chemistry

Pharmacological effects of antidepressants are based upon blocking (inhibiting) the enzyme that acts as a catalyst for the breakdown of biogenic amines noradrenalin and serotonin in the mitochondria of cephalic neurons. What enzyme takes part in this process?

  1. A. Monoamine oxidase
  2. B. Transaminase
  3. C. Decarboxylase
  4. D. Peptidase
  5. E. Lyase
Hint

Ask what type of chemical reaction inactivates noradrenaline and serotonin in mitochondria, then identify the enzyme class that catalyses it.

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