KROK 1 2012 – Question 191 · KROK (Medicine) · Biological Chemistry

A male patient has been diagnosed with acute radiation disease. Laboratory examination revealed a considerable reduction of platelet serotonin level. The likely cause of platelet serotonin reduction is the disturbed metabolism of the following substance:

  1. A. 5-oxytryptofane
  2. B. Phenylalanine
  3. C. Serine
  4. D. Histidine
  5. E. Tyrosine
Hint

Think about the biosynthetic pathway by which platelets and other cells build serotonin step by step from an amino acid.

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