KROK 1 2011 – Question 160 · KROK (Medicine) · Pathomorphology
A 70-year-old male patient died from acute coronary insufficiency. He had knee joint swelling, gonycampsis and gonalgia during his lifetime. Pathomorphologic examination of the deformed joints and synovial membranes revealed membrane hyperaemia with multiple perivascular inflammatory infiltrations made by lymphocytes, plasmocytes and macrophagocytes. There was an accumulation of organized fibrin covering some areas of synovium membrane and looking like rice grains in the articular liquid. What is the most likely diagnosis?
- A. Periarteritis nodosa
- B. Deforming arthrosis
- C. Atrophic arthritis
- D. Tuberculous arthritis
- E. Ankylosing spondylitis
Hint
Consider the cell types, the chronicity of the synovial inflammation and the fibrin bodies in the joint fluid, and decide whether the process is degenerative, infectious or autoimmune.
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