KROK 1 2011 – Question 156 · KROK (Medicine) · Pathomorphology
A patient with high-titer antinuclear antibodies died from progressing renal impairment. Autopsy revealed mesangioproliferative glomerulonephritis and abacterial polypous endocarditis. There was periarterial bulbar sclerosis in spleen and productive proliferative vasculitis in skin. What is the most likely diagnosis?
- A. Dermatomyositis
- B. Nephrotic syndrome
- C. Rheumatism
- D. Periarteritis nodosa
- E. Systemic lupus erythematosus
Hint
Combine the antinuclear antibodies with the pattern of kidney, non-infective valve, splenic and skin lesions and ask which multisystem autoimmune disease explains all of them together.
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