KROK 1 2011 – Question 192 · KROK (Medicine) · Pathomorphology

The liver puncture biopsy of a patient with hepatocellular insufficiency revealed hydropic and ballooning degeneration of hepatocytes, necrosis of certain cells, presence of Kaunsilmen’s bodies. Portal and lobular stroma were infiltrated mostly with lymphocytes and macrophages as well as with a small number of polymorphonuclear lymphocytes. What is the most likely diagnosis?

  1. A. Acute viral hepatitis
  2. B. Alcoholic hepatitis
  3. C. Chronic aggressive hepatitis
  4. D. Autoimmune hepatitis
  5. E. Chronic persistent hepatitis
Hint

Use the hepatocyte injury pattern (swelling, ballooning, scattered cell death) and the lymphomacrophagic infiltrate to judge how long the process has lasted and what is likely behind it.

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