KROK 1 2012 – Question 25 · KROK (Medicine) · Pathomorphology

Microscopic examination of the enlarged neck gland of a 14 year old girl revealed destruction of the tissue structure of the node, absence of the lymph follicles, sclerotic areas and necrosis foci, cell constitution of the node is polymorphous, lymphocytes, eosinophiles, big atypical cells with multilobular nuclei (Beresovsky-Sternberg cells) and mononuclear cells of the large size are present. What is the most likely diagnosis?

  1. A. Acute lympholeucosis
  2. B. Fungoid mycosis
  3. C. Berkitt’s lymphoma
  4. D. Lymphogranulomatosis
  5. E. Chronic lympholeucosis
Hint

Consider the polymorphous cell background with scarring and the characteristic large atypical cells described, and compare that with monotonous proliferations of lymphoid cells.

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