KROK 1 2012 – Question 15 · KROK (Medicine) · Pathomorphology

Autopsy of a 58 year old man revealed that bicuspid valve was deformed, thickened and unclosed. Microscopically: foci of collagen fibrilla are eosinophilic, react positively to fibrin. The most probably it is:

  1. A. Amyloidosis
  2. B. Hyalinosis
  3. C. Fibrinous inflammation
  4. D. Fibrinoid swelling
  5. E. Mucoid swelling
Hint

Ask what has happened to the collagen fibres of this valve, and compare reversible changes of the ground substance with irreversible destruction of the fibres themselves.

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