KROK 1 2021 – Question 126 · KROK (Medicine) · Pathophysiology

A woman with chronic hepatitis complains of increased sensitivity to barbiturates that previously she could take without any signs of intoxication. Her condition is mainly associated with disturbance of the following hepatic function:

  1. A. Phagocytic
  2. B. Hemodynamic
  3. C. Metabolic
  4. D. Hematopoietic
  5. E. Bile formation
Hint

Think about where the body inactivates lipophilic sedative drugs, and what happens to their blood level and duration of action when that organ's enzyme capacity is reduced.

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