KROK 1 2021 – Question 135 · KROK (Medicine) · Pathophysiology

A man, who has arrived from Tunisia, has alpha-thalassemia with hemolysis of erythrocytes and jaundice. The disease was diagnosed based on the presence of the following in the patient’s blood:

  1. A. Polychromatophilic erythrocytes
  2. B. Target erythrocytes
  3. C. Granular erythrocytes
  4. D. Normocytes
  5. E. Reticulocytes
Hint

Think about the characteristic red cell shape on a blood smear in thalassemia, where reduced globin synthesis leaves cells pale with excess membrane relative to haemoglobin.

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