KROK 1 2021 – Question 120 · KROK (Medicine) · Pharmacology
In the hematology unit a patient with leukemia was prescribed 5-fluorouracil. This drug:
- A. Inhibits DNA synthesis
- B. Inhibits translation
- C. Inhibits transcription
- D. Catalyzes replication
- E. Stimulates DNase
Hint
5-Fluorouracil is a pyrimidine antimetabolite; think which nucleotide synthesis its metabolite blocks and which macromolecule is therefore deprived of building blocks.
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