KROK 1 2008 – Question 14 · KROK (Medicine) · Pharmacology

A patient with frequent attacks of stenocardia was prescribed sustak-forte to be taken one tablet twice a day. At first the effect was positive but on the second day stenocardia attacks resumed. What can explain inefficiency of the prescribed drug?

  1. A. Tachyphylaxis
  2. B. Cumulation
  3. C. Dependence
  4. D. Sensibilization
  5. E. Idiosyncrasy
Hint

Think about what happens to the effect of a nitrate-type vasodilator when the same dose is repeated within a short time after a good first response.

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