KROK 1 2008 – Question 49 · KROK (Medicine) · Pharmacology

A patient taking clonidine for essential hypertension treatment was using alcohol that caused intense inhibition of central nervous system. What may it be connected with?

  1. A. Idiosyncrasy
  2. B. Intoxication
  3. C. Effect potentiating
  4. D. Cumulation
  5. E. Effect summation
Hint

Clonidine itself has a sedative action through central alpha-2 receptors; consider how the listed interaction terms differ in whether the combined effect equals, exceeds or merely prolongs the separate effects.

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