KROK 1 2021 – Question 107 · KROK (Medicine) · Pathophysiology

A 48-year-old woman with diabetes mellitus has been hospitalized in a severe precomatose state. Analysis of her acid-base balance revealed metabolic acidosis. What primary mechanism is the cause of the changes detected in the woman's acid-base balance?

  1. A. Disturbed utilization of O₂ in the cells
  2. B. Disturbed blood buffer systems
  3. C. Decreased CO₂ excretion
  4. D. Excretion of alkaline components with urine
  5. E. Formation of underoxidized products
Hint

Think about which acidic metabolites accumulate when insulin deficiency forces the liver to break down fatty acids in large amounts.

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