KROK 1 2021 – Question 106 · KROK (Medicine) · Pathomorphology

A man, who for many years has been suffering from bronchial asthma, has died of asphyxia. Histology of his lungs shows large amounts of mucus with eosinophilic admixtures in the lumina of the bronchioles and small bronchi, the interalveolar septa are sclerotic, the alveolar lumina are dilated. What mechanism of hypersensitivity reaction development is observed in this case?

  1. A. Reagin reaction
  2. B. Cytotoxic reaction
  3. C. Granulomatosis
  4. D. Immune complex reaction
  5. E. Lymphocyte-induced cytolysis
Hint

Think about which immediate-type allergic mechanism produces eosinophil-rich mucus plugs and chronic airway remodelling in asthma.

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