KROK 1 2021 – Question 147 · KROK (Medicine) · Pathomorphology
A man for a long time was suffering from hemoblastosis. Autopsy of the body revealed brown color of the bone marrow, spleen, liver, and lymph nodes. Perls histochemical reaction was performed. It was determined that reticular, endothelial, and histiocytic elements of the affected organs contain blue granules. What pigment was detected using the Perls histochemical reaction?
- A. Bilirubin
- B. Hematoporphyrin
- C. Hematoidin
- D. Hemosiderin
- E. —
Hint
The Perls reaction stains iron; think about which iron-containing pigment derived from haemoglobin accumulates in macrophages when red cells are broken down in excess.
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