KROK 1 2021 – Question 81 · KROK (Medicine) · Pathomorphology
Autopsy of the body of a 40-year-old woman, who died of uremia, shows enlarged variegated kidneys. In the kidneys, the glomerular capillary membranes are thickened and resemble «wire loops»; there are foci of fibrinoid necrosis in their walls and hyaline thrombi in their lumina. In the nuclei, there are hematoxylin bodies. In the heart, Libman-Sacks endocarditis is observed. What renal disorder is the most likely in this case?
- A. Cholera glomerulonephritis
- B. Sclerotic kidney
- C. Rheumatic glomerulonephritis
- D. Lupus nephritis
- E. Terminal glomerulonephritis
Hint
Wire-loop capillaries, hematoxylin bodies and verrucous lesions on the heart valves point to a systemic autoimmune disease with renal involvement.
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