KROK 1 2021 – Question 1 · KROK (Medicine) · Pathomorphology
When examining a biopsy material obtained from the thyroid gland, the pathologist discovered lymphocyte infiltration of the thyroid tissues and destruction of the parenchymal elements. Diffuse lymphocyte infiltration with lymphoid follicles was detected in the stroma. What is the most likely diagnosis?
- A. Graves’ disease (toxic diffuse goiter)
- B. Solid adenoma of the thyroid
- C. Papillary thyroid cancer
- D. Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis)
- E. Undifferentiated thyroid carcinoma
Hint
Think of an autoimmune process in which the gland is gradually replaced by lymphoid follicles while the follicular epithelium is progressively lost.
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