KROK 1 2023 – Question 134 · KROK (Medicine) · Pathomorphology

Postmortem examination of the fetus from the second pregnancy of an Rh-negative mother is being performed. The fetus died in utero at 7 months of pregnancy. Autopsy detects diffuse edema of the subcutaneous tissue and brain, ascites, enlarged liver and spleen, thymic atrophy, and myocardial hypertrophy. Microscopy reveals centers of extramedullary hematopoiesis, as well as dystrophic and necrobiotic changes in internal organs. What form of hemolytic disease corresponds with these pathological changes?

  1. A. Edematous form
  2. B. Anemic form
  3. C. Congenital icteric form
  4. D. Postpartum icteric form
  5. E. —
Hint

Compare the forms of Rh hemolytic disease by severity and timing: which one can already cause fetal death before birth, and which ones appear only after delivery?

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