KROK 1 2021 – Question 38 · KROK (Medicine) · Pathomorphology
X-ray has detected multiple foci of osteoporosis and osteolysis in the flat bones of a man. Trephine biopsy material contains high levels of neoplastic plasma cells. Make the diagnosis:
- A. Chronic myeloid leukemia
- B. Histiocytosis
- C. Multiple myeloma
- D. Lymphogranulomatosis
- E. Acute monocytic leukemia
Hint
Focus on the cell type that proliferates in the biopsy and on the punched-out lytic bone lesions that such cells provoke through osteoclast activation.
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