KROK 1 2023 – Question 100 · KROK (Medicine) · Pathomorphology
A 47-year-old woman has interphalangeal and metacarpophalangeal joints that can be easily dislocated or subluxated and a characteristic deviation of the fingers that resembles "walrus flippers". Microscopy reveals proliferation of synovial villi, cartilage destruction, and pannus formation. What disease causes these pathological changes?
- A. Ankylosing spondylitis (Bekhterev’s disease)
- B. Rheumatoid arthritis
- C. Osteoarthrosis
- D. Rheumatic arthritis
- E. Systemic lupus erythematosus
Hint
Symmetric small-joint polyarthritis with hand deformities, villous synovial proliferation and a layer of granulation tissue over cartilage point to a chronic autoimmune joint disease.
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