KROK 1 2023 – Question 6 · KROK (Medicine) · Biological Chemistry
Examination of a patient shows decreased leukocyte and erythrocyte count and low hemoglobin levels in the peripheral blood, as well as appearance of large cells (megaloblasts). What vitamin is likely to be deficient in this case, causing this condition?
- A. Biotin
- B. Niacin
- C. Ascorbic acid
- D. Folic acid
- E. Riboflavin
Hint
Megaloblastic changes with pancytopenia reflect impaired DNA synthesis in dividing marrow cells; consider which vitamin supplies one-carbon units for thymidylate formation.
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