KROK 1 2023 – Question 17 · KROK (Medicine) · Biological Chemistry

Bioactive substances hormones are produced as a result of hydrolysis and modification of certain proteins. What protein in the pituitary gland is the source of lipotropin, corticotropin, melanotropin, and endorphin?

  1. A. Neurostromin
  2. B. Proopiomelanocortin (POMC)
  3. C. Neuroalbumin
  4. D. Thyroglobulin
  5. E. Neuroglobulin
Hint

Several pituitary peptides share a single large precursor protein that is cleaved in a tissue-specific way by prohormone convertases.

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