KROK 1 2023 – Question 20 · KROK (Medicine) · Biological Chemistry

A 7-year-old child was diagnosed with anemia. Laboratory testing detects pyruvate kinase deficiency in the erythrocytes. What process is disturbed in this case, playing the main role in the anemia development?

  1. A. Gluconeogenesis
  2. B. Anaerobic glycogenolysis
  3. C. Amino acid decarboxylation
  4. D. Anaerobic glycolysis
  5. E. Amino acid deamination
Hint

Mature erythrocytes lack mitochondria, so consider which pathway is their only source of ATP and how its last step is blocked.

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