KROK 1 2020 – Question 121 · KROK (Medicine) · Biological Chemistry
A patient is diagnosed with glucocerebroside lipidosis (Gaucher’s disease) that manifests as splenomegaly, liver enlargement, affected bone tissue, and neuropathies. What enzyme of complex lipid catabolism is deficient, causing this disease?
- A. Hyaluronidase
- B. Glucocerebrosidase
- C. β-galactosidase
- D. Sphingomyelinase
- E. Hexosaminidase
Hint
Work out which lipid is accumulating from the name of the disease, and ask which lysosomal hydrolase acts on that particular substrate.
The answer, the explanation and a note on every option are available once you log in. The account is free: topic tests, a mock exam, mistake review and statistics.
More questions on Biological Chemistry
- A patient has frequent visceral and mucosal hemorrhages. Analysis shows that the collagen fibers in the patient’s body lack hydroxyproline and…
- A patient presents with acute attack of choledocholithiasis. Laboratory examination of the patient’s feces will likely to show the following in this…
- Examination of a patient shows decreased leukocyte and erythrocyte count and low hemoglobin levels in the peripheral blood, as well as appearance of…
- A 15-year-old patient complains of general weakness, dizziness, and rapid fatigability. Examination detects changed shape of erythrocytes and…
- In the nucleus of a cell, a molecule of mature mRNA, which is smaller in size, was formed from a larger molecule of immature mRNA. The stages of…
- Bioactive substances hormones are produced as a result of hydrolysis and modification of certain proteins. What protein in the pituitary gland is…