KROK 1 2020 – Question 40 · KROK (Medicine) · Biological Chemistry

It is a known fact that in the human body the biosynthesis of purine nucleotides occurs de novo from amino acids. Name the amino acids that are used in the synthesis of the purine nucleotide cycle:

  1. A. Methionine, tryptophan, alanine
  2. B. Isoleucine, serine, valine
  3. C. Proline, tyrosine, phenylalanine
  4. D. Leucine, glutamine, cysteine
  5. E. Glycine, aspartate, glutamine
Hint

Recall the small precursors, amino acids among them, whose atoms are assembled step by step into the purine ring on a ribose phosphate scaffold.

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