KROK 1 2020 – Question 67 · KROK (Medicine) · Biological Chemistry
Vitamin B1 deficiency impairs oxidative decarboxylation of alpha-ketoglutaric acid, which leads to disturbed synthesis of a certain coenzyme. Name this coenzyme:
- A. Lipoic acid
- B. Nicotinamide adenine dinucleotide (NAD)
- C. Flavin adenine dinucleotide (FAD)
- D. Coenzyme A
- E. Thiamine pyrophosphate (TPP)
Hint
Ask which cofactor of the α-ketoglutarate dehydrogenase complex is made directly from the vitamin named in the stem, rather than from other vitamins or by the body itself.
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