KROK 1 2020 – Question 51 · KROK (Medicine) · Biological Chemistry
A woman complains that her child is unwell: the child developed loss of appetite, insomnia, and irritability. Biochemical testing shows that there is no glucocerebrosidase enzyme in the child’s blood. It is characteristic of the following pathology:
- A. Gaucher disease
- B. Von Gierke disease (glycogen storage disease type I)
- C. Pompe disease (glycogen storage disease type II)
- D. Tay-Sachs disease
- E. Niemann-Pick disease
Hint
Work out which lipid the named enzyme normally breaks down in lysosomes, then match the resulting storage pattern to the listed disorders.
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