KROK 1 2019 – Question 105 · KROK (Medicine) · Pathomorphology

Autopsy of a 30-year-old man shows enlarged spleen (weight - 900.0 g), enlarged liver (weight - 4000.0 g), and enlarged lymph nodes. Bone marrow of the femoral shaft is bright red and moist. Microscopically in the liver there are thick infiltrates located mostly along the portal tract. The infiltrates consist of juvenile hemopoietic cells with round nuclei and thin layer of cytoplasm. What disease can be suspected?

  1. A. Chronic lymphocytic leukemia
  2. B. Generalized lymphogranulomatosis
  3. C. Acute myeloblastic leukemia
  4. D. Acute lymphoblastic leukemia
  5. E. Chronic myeloid leukemia
Hint

Judge the maturity of the infiltrating cells and the pattern in which they spread through the liver, then consider which cell lineage and age group fit.

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