KROK 1 2019 – Question 113 · KROK (Medicine) · Pathomorphology
A patient has gradually developed a skin plaque on his face. In the center of this plaque there are necrotic patch and an ulcer. Histopathological analysis of the biopsy material reveals proliferation of atypical epithelial cells with large number of pathologic mitoses. What is the most likely diagnosis?
- A. Skin cancer
- B. Trophic ulcer
- C. Papilloma
- D. Sarcoma
- E. Fibroma
Hint
Combine the slow growth, central ulceration and necrosis with the cell type and mitotic activity seen on histology to decide whether the lesion is benign or malignant and from which tissue it arises.
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