KROK 1 2019 – Question 137 · KROK (Medicine) · Pathomorphology

Autopsy of a 49-year-old woman who died of chronic kidney failure shows small dense striated kidneys with areas of hemorrhages. Microscopically nuclei of epithelial channels contain hematoxylin bodies; glomerular capillaries resemble wire loops, have thickened basement membranes, and in places contain hyaline thrombi and foci of fibrinoid necrosis. What is the most likely diagnosis?

  1. A. Arteriolosclerotic nephrosclerosis
  2. B. Atherosclerotic nephrosclerosis
  3. C. Rheumatism
  4. D. Systemic lupus erythematosus
  5. E. Amyloidosis
Hint

Concentrate on the pair of findings, hematoxylin bodies and wire-loop glomerular capillaries, and ask which of the listed diseases is known for both in the kidney.

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