KROK 1 2018 – Question 61 · KROK (Medicine) · Pharmacology
A 56-year-old man complains of thirst and frequent urination. The endocrinologist diagnosed this patient with diabetes mellitus and prescribed him glibenclamide. What mechanism of action does this drug have?
- A. Suppression of α-cells of islets of Langerhans
- B. Facilitates glucose uptake by the tissues
- C. Facilitates glucose transport through cell membranes
- D. Stimulation of β-cells of islets of Langerhans
- E. Inhibits glucose absorption in the intestine
Hint
Think about the cellular target of a sulfonylurea in the pancreas and whether it promotes or limits release of a hormone.
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